5 Steps Of Endochondral Ossification
Question: Step 1
Answer: Cartilage enlarges; Chondrocytes die
Question: Step 2
Answer: blood vessels grow into perichondrium; cells convert to osteoblasts; shaft becomes covered with superficial bone
Question: Step 3
Answer: more blood supply and osteoblasts; produces spongy bone; formation spreads on shaft
Question: Step 4
Answer: Osteoclasts create medullary cavity; appositional growth
Question: Step 5
Answer: epiphysis centers calcify; blood and osteoblasts move in; secondary ossification centers